Chronic Liver Disease

Chronic Liver Disease /Cirrhosis

What is Chronic Liver Disease?

The liver is essential for digesting food and clearing your body of toxic substances. Cirrhosis is when scar tissue supplants healthy liver tissue. This prevents the liver from working normally. Cirrhosis is defined as long-term (chronic) liver disease. The loss to your liver builds up over time.

Our liver is the body’s largest internal organ. It placed under our ribs on the right side of your belly. The liver performs many important things including:

  • Waste removal from the body, such as toxins and medicines
  • Making bile to help digest food
  • Storing sugar that the body uses for energy
  • Making new proteins.

When you are diagnosed with cirrhosis, scar tissue slowdowns the flow of blood through the liver. Over time, the liver can’t perform the way it should do. In some cases, the liver is damaged so badly that it stops functioning. This causes liver failure. 

Dr. Chetan Kalal is Chronic Liver disease specialist in South Mumbai, he is associated with Sir HN Reliance Foundation Hospital and Research Centre. Let see what causes cirrhosis.

What causes liver disease?


Parasites and viruses can infect the liver, causing inflammation that reduces liver function. The viruses that cause liver damage can be spread through blood or semen, contaminated food or water, or close contact with a person who is infected. The most common types of liver infection are hepatitis viruses, including:

  • Hepatitis A
  • Hepatitis B
  • Hepatitis C

Immune system abnormality

Diseases in which your immune system attacks certain parts of your body (autoimmune) can affect your liver. Examples of autoimmune liver diseases include:

  • Autoimmune hepatitis
  • Primary biliary cholangitis
  • Primary sclerosing cholangitis


An abnormal gene inherited from one or both of your parents can cause various substances to build up in your liver, resulting in liver damage. Genetic liver diseases include:

  • Hemochromatosis
  • Wilson’s disease
  • Alpha-1 antitrypsin deficiency

Cancer and other growths

Examples include:

  • Liver cancer
  • Bile duct cancer
  • Liver adenoma


Additional, common causes of liver disease include:

  • Chronic alcohol abuse
  • Fat accumulation in the liver (nonalcoholic fatty liver disease)
  • Certain prescription or over-the-counter medications
  • Certain herbal compounds

What are the symptoms of cirrhosis/ liver disease?

Liver disease doesn’t always cause noticeable signs and symptoms. If signs and symptoms of liver disease do occur, the may include:

  • Skin and eyes that appear yellowish (jaundice)
  • Abdominal pain and swelling
  • Swelling in the legs and ankles
  • Itchy skin
  • Dark urine color
  • Pale stool color
  • Chronic fatigue
  • Nausea or vomiting
  • Loss of appetite
  • Tendency to bruise easily

How is cirrhosis treated?

Being Chronic Liver disease specialist in South Mumbai, Dr. Chetan Kalal will determine specific Liver disease treatment for cirrhosis based on: